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Understanding Blood Stem Cell Transplants


National Cancer Institute

Title Page

1. Stem Cells

2. Blood Stem Cells

3. From Bone Marrow to the Bloodstream

4. Blood Stem Cell Transplants: When?

5. Stem Cells from Self to the Rescue

6. Stem Cells from Donor to the Rescue

7. Not Just Any Blood Stem Cells Will Do

8. Host vs. Graft/Graft vs. Host

9. Tissue Typing Matches Donors to Patients

10. Many Names for the "Self" Antigens

11. Haplotypes: Passing on Genes for "Self" Antigens

12. 6 Major Genes: 10,000 Antigens

13. Three Most Important Antigens

14. A "Clinical Match"

15. Some Haplotypes Occur More Often

16. Sometimes a 3-Antigen Match Is Necessary

17. A Delicate Balance: Graft vs. Tumor/Graft vs. Host

18. Success in Matching Varies With Population

19. Preparing Patients for Myeloablative Allogeneic Transplants

20. Preparing Patients for Reduced-Intensity Allogeneic Transplants

21. Preparing Donors for Allogeneic Transplants

22. Apheresis: Harvesting Stem Cells From Peripheral Blood

23. Preparing Patients for Autologous/Syngeneic Transplants

24. Cord Blood as a Source of Stem Cells

25. Placental and Cord-Blood Stem Cell Transplants

26. Using More Than One Cord-Blood Donor

27. Placental and Cord-Blood Transplants: Pros and Cons

28. New Development: Stockpiling

29. When a Blood Stem Cell Transplant Works

30. National Marrow Donor Program Helps Many