30. Smoking and Susceptibility to Lung Cancer - SNPs in Detoxifying Proteins
SNPs may also influence detoxifying enzymes that prepare carcinogens for elimination from the human body. SNPs that result in very active forms of detoxifying enzymes will remove the carcinogens quickly from the body, allowing less time for damage.
SNPs that produce sluggish detoxifying enzymes will permit carcinogens to remain in the body for a longer time.